Oscar Isaac voices Miguel O’Hara, canonically known as Spider-Man 2099 from Earth-928. As the head of the interdimensional Spider-Gang, Miguel is in charge of the Super-Collider, a particle accelerator designed to bridge the gap between dimensions. As with all Spider-Men, Miguel has a dark past that has left him strong-headed and resentful. In addition to heading the superhero multiverse, he acts as a main antagonist in the film.
In an interview with Rolling Stone, producers Philip Lord and Chris Miller revealed that Isaac only agreed to voice Miguel on the condition that they did not make his character boring. In an attempt to flesh out his backstory, they took inspiration from Isaac’s real-life experiences.
“One of the things we talked about with Oscar was like, we know people in our lives that are hardliners, right?” Lord said. “And what makes them a hardliner is, they’re mostly traumatized. And the only way out is through a kind of orthodoxy. Because you can’t tolerate dissent, because dissent is to question whether your pain is legitimate or not. Oscar is from an exile community of Cubans, and that’s a lot of how people feel. And we were like, well, let’s expose the beginnings of that trauma, and so you’re sort of rooting for Miguel to find some other way. Because this was not working for him.”