A hidden Alzheimer’s tipping point may decide who gets dementia

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Researchers from VIB, KU Leuven, the UK-DRI and Muna Therapeutics, with funding that included support from ERC, have identified a major biological shift that may help determine whether Alzheimer's disease changes in the brain eventually lead to dementia.

Using donated brain tissue from older adults with and without cognitive decline, along with samples from cognitively healthy centenarians, the team uncovered distinct cellular programs and immune cell states l...

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