A hidden immune loop may drive dangerous inflammation with age

As people grow older, the immune system often becomes less balanced and more prone to dysfunction. This shift can leave older adults more vulnerable to serious conditions such as sepsis. New research from scientists at the University of Minnesota sheds light on why this happens, showing how certain immune cells called macrophages remain locked in an inflammatory state as the body ages in preclinical models. The study was published today in Nature Aging.

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