A major Alzheimer’s risk gene may shrink brain cells years before symptoms

13 hours ago 8

Millions of people carry APOE4, the strongest known genetic risk factor for Alzheimer's disease. New research suggests the gene variant may begin altering brain activity well before memory problems become noticeable.

Researchers at Gladstone Institutes have now mapped out a molecular sequence that could help explain these early effects. Their findings also point to a possible way to reverse some of the changes.

In a study using mouse models, published i...

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