Columbia scientists discover surprising link between serotonin and heart valve disease

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Serotonin is usually associated with mood, sleep, and digestion. But research published in 2023 suggests this chemical messenger may also influence a small structure that performs a vital job during every heartbeat: the mitral valve.

The multicenter investigation found evidence that reduced activity of the serotonin transporter may accelerate damaging changes in valves already affected by degenerative mitral regurgitation (DMR). Researchers at Columbia Univers...

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