Scientists inject one tumor and watch cancer vanish across the body

For more than two decades, scientists have explored a group of cancer drugs known as CD40 agonist antibodies. Early experiments suggested these treatments could strongly activate the immune system and help it destroy cancer cells. However, results in people were disappointing. Clinical trials showed only modest benefits, and the drugs often caused serious side effects such as widespread inflammation, dangerously low platelet levels, and liver damage. These reactions occurred even a...