Scientists may have found a shortcut to calorie restriction’s anti-aging benefits

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Reducing calorie intake has extended lifespan in animals including mice, rhesus monkeys, and fruit flies. In some studies, the animals also remained healthier for longer. But severe calorie restriction can come with serious costs. Mice placed on a diet with 40% fewer calories, for instance, become more vulnerable to infections, reproduce less successfully, and show impaired growth.

That has left scientists with a difficult question: Could humans gain some of t...

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