Scientists were wrong for decades about DNA knots

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Scientists at the University of Cambridge, working with international collaborators, have identified a crucial process that shapes how DNA behaves as it moves through nanoscale pores. This process is fundamental to many biological activities and to fast-growing DNA sensing technologies. The research highlights a long-overlooked DNA structure called plectonemes, a finding that could influence future advances in genomics and biosensing.

Nanopores are extremely s...

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